"Determination of total and free testosterone in serum and saliva in patients having obstructive sleep apnea"
Project leader: Assoc. Prof. Diana Petkova, MD, PhD and Yana Bocheva, PhD
The project aimed:
1. Validation of: reference method for determining total testosterone (tt); immunoassay for determining of free testosterone (ft) in men and tt in women and children; a protocol for deliverind an utrafiltrate and saliva for ft determinaing.
2. Making a reference range for ft in saliva.
3. Evaluating of: hipothetic hypogadism in in patients having obstructive sleep apnea(osa); the effect of treatment upon the levels of tt and ft in serum and saliva; correlation between the levels of ft in saliva and serum.